Flt1/VEGFR1 heterozygosity causes transient embryonic edema

Flt1/VEGFR1 heterozygosity causes transient embryonic edema

Vascular endothelial growth factor-A is a major player in vascular development and a potent vascular permeability factor under physiological and pathological conditions by binding to a decoy receptor Flt1 and its primary receptor Flk1. In this study, we show that Flt1 heterozygous (Flt1(+/-)) mouse embryos grow up to adult without life-threatening abnormalities but exhibit a transient embryonic...

Pathophysiology of Transient Corneal Edema and Pseudophakic Cystoid Macular Edema

Dear Editor, We read with interest the article titled “Transient corneal edema is a predictive factor for pseudophakic cystoid macular edema after uncomplicated cataract surgery” [1], in which the authors found that transient corneal edema (TCE) following cataract surgery is a predictive factor of pseudophakic cystoid macular edema (PCME). The study was well designed and conducted and answered ...

Infectious causes of embryonic and fetal mortality.

The purpose of this review is to summarize bacterial, fungal, protozoan, and viral causes of reproductive dysgenesis in cattle, sheep, goats, pigs, horses, dogs, and cats. The clinical presentations of disease due to reproductive pathogens are emphasized, with a focus on assisting development of complete lists of causes that result in abortion and infertility in these species. Clinicians are en...

Transient Embryonic Antigens in the Chick.

Effect of pentoxifylline on brain edema in a rat model of transient focal cerebral ischemia

Pervious studies have shown that pentoxifylline (PTX) has beneficial effects in reduction of stroke and brain trauma injuries in experimental animals. However, there is very little and controversial information about the effect of PTX on brain edema in cerebral ischemia. Therefore, the aim of this study was to determine the effects of different doses of PTX on brain edema and neurological m...